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Anthony Yezzi School of Electrical and Computer Engineering Georgia Institute of Technology
Part I: A PDE approach for measuring tissue thickness
We outline an Eulerian framework for computing the thickness of tissues between two simply connected boundaries. Thickness is defined as the length of trajectories which follow a smooth vector field constructed in the region between the boundaries. A pair of partial differential equations (PDE's) are then solved and combined to yield length without requiring the explicit construction of the trajectories. An efficient, stable, and computationally fast solution to these PDE's is found by careful selection of finite differences according to an upwinding condition.
Part II: Shape Priors and Region Based Active Contours
We propose a model-based curve evolution technique for segmentation of images containing known object types. In particular, motivated by the work of Leventon, Grimson, and Faugeras, we derive a parametric model for an implied representation of the segmenting curve by applying principal component analysis to a collection of signed distance representations of the training data. The parameters of this representation are then calculated to minimize an objective function for segmentation. We found the resulting algorithm to be computationally efficient, able to handle multidimensional data, robust to noise and initial contour placements, while at the same time, avoiding the need for point correspondences during the training phase of the algorithm.
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